Most primary rectal cancers are adenocarcinomas, of which most are conventional gland-forming tumors (Fig. 4.3a, b). However, some special types need to be … See more Adenocarcinomas are graded predominantly based on the extent of glandular appearance. Despite a significant degree of interobserver variability, histologic grade … See more Despite interobserver variability and absence of specific definition and diagnostic criteria, the nature of the advancing tumor margin and degree of lymphocytic … See more Identification of microsatellite instability-high (MSI-H) colorectal tumors is important, as DNA mismatch repair deficiency may serve as a prognostic marker of patient … See more Tumor budding is described as the presence of detached single cells or clusters of up to 4 or 5 cells (Fig. 4.5a, b) along the invasive tumor front [47]. In contrast to … See more WebThis button displays the currently selected search type. When expanded it provides a list of search options that will switch the search inputs to match the current selection.

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