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Thiosulfate toxicity

WebFeb 21, 2024 · irritability. loss of appetite. lower back or side pain. mood changes. muscle pain, cramps, or twitching. nausea. numbness or tingling in the hands, feet, or lips. painful … WebOct 3, 2024 · Sodium thiosulfate is a medication used as an antidote to cyanide poisoning. Sodium thiosulfate is sequentially administered as an intravenous (IV) injection after …

Thiosulfate - Wikipedia

WebJun 21, 2024 · Sodium thiosulfate was associated with few high-grade toxic effects. The absolute hearing threshold was assessed in 101 children. Hearing loss of grade 1 or higher occurred in 18 of 55 children ... WebSilver thiosulfate, a highly soluble compound and main component of wastewaters of photoprocessors, has a very low toxicity (e.g., it is 15,000–17,000 times less toxic than … roblox high school roleplay https://smt-consult.com

SAFETY DATA SHEET

Sodium thiosulfate (sodium thiosulphate) is an inorganic compound with the formula Na2S2O3·xH2O. Typically it is available as the white or colorless pentahydrate, Na2S2O3·5H2O. The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water. Sodium thiosulfate is used in gold mining, water treatment, analytical chemistry, … WebNo malformations or evidence of embryo-fetal toxicity were noted when pregnant mice, rats, hamsters, or rabbits were administered oral doses of sodium thiosulfate of up to 550, 400, 400, or 580 mg/kg, respectively during organogenesis (0.2, 0.3, 0.26, and 0.9 times the human dose of 12.5 g/60 kg person for cyanide poisoning based on body ... WebJun 21, 2024 · Sodium thiosulfate was associated with few high-grade toxic effects. The absolute hearing threshold was assessed in 101 children. Hearing loss of grade 1 or higher occurred in 18 of 55 children (33%) in the cisplatin-sodium thiosulfate group, as compared with 29 of 46 (63%) in the cisplatin-alone group, indicating a 48% lower incidence of ... roblox high school life codes 2023

Thiosulfate - an overview ScienceDirect Topics

Category:Sodium Thiosulfate for Protection from Cisplatin-Induced

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Thiosulfate toxicity

Sodium Thiosulfate: Uses, Warnings, Side Effects, Dosage

WebNov 2, 2009 · In soil, sewage sludge, and sediments, in which silver sulfide predominates, the toxicity of silver, even at high total concentrations, is very low. The highly soluble silver thiosulfate complex has low toxicity, which can be attributed to the silver complexed by thiosulfate. Silver nitrate is one of the most toxic silver compounds. WebCyanide Poisoning. Comprehensive treatment of acute cyanide intoxication requires support of vital functions; administration of sodium nitrite and sodium thiosulfate should be …

Thiosulfate toxicity

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WebIt can be used alone to treat mild to moderately severe cyanide poisoning, but it should be combined with additional antidotes such as hydroxocobalamin in situations of severe cyanide poisoning. Even though sodium thiosulfate is an inadequate antidote for acute cyanide poisoning due to weak intracellular penetration, a sluggish start of the ... WebMay 24, 2024 · One strategy that has helped combat cyanide toxicity in patients receiving high doses or prolonged infusions of nitroprusside involves the co-administration of …

WebSodium Thiosulfate Injection is indicated for sequential use with sodium nitrite for the treatment of acute cyanide poisoning that is judged to be serious or life- threatening. … WebFeb 1, 2024 · Descriptions. Sodium thiosulfate may be used to lessen some of the side effects of cisplatin (a cancer medicine). It is also used with another medicine in the …

WebThiosulfate is an important intermediate as it can act as an electron acceptor or donor and thus mediate both oxidative and reductive cycle. Thus the thiosulfate shunt provides for complete anaerobic sulfur cycling. ... (site of cellular toxicity). The thiosulfate provides the sulfur source by which the cyanide becomes bound and then excreted ... WebSep 20, 2024 · The incidence of hearing loss was lower in the sodium thiosulfate and cisplatin arm (39%) compared with the cisplatin alone arm (68%); unadjusted relative risk 0.58 (95% CI: 0.40, 0.83).

WebOct 20, 2024 · Sodium nitrite and sodium thiosulfate. Sodium nitrite and sodium thiosulfate are often used in combination and are currently considered second-line therapy after …

WebFeb 1, 2024 · Sodium thiosulfate may be used to lessen some of the side effects of cisplatin (a cancer medicine). It is also used with another medicine in the emergency treatment of cyanide poisoning. Sodium thiosulfate is also used to reduce the risk of hearing loss in children 1 month of age and older who are receiving medicines (eg, cisplatin) for cancer ... roblox high school money scriptWebRizwan A. Qazi, Kevin J. Martin, in Therapy in Nephrology & Hypertension (Third Edition), 2008 Sodium Thiosulfate. There are case reports of using sodium thiosulfate (STS) with apparent healing of the ulcers. 35, 36 STS is an antidote for cyanide and cisplatin toxicity and has antioxidant properties. The solubility of calcium thiosulfate in aqueous solutions … roblox high school skateboardWebProduct name : Sodium thiosulfate Product Number : 217263 Brand : SIGALD CAS-No. : 7772-98-7 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Synthesis of substances ... Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - > 100 mg/l - 72 h roblox high school smiling girl codeWebNational Center for Biotechnology Information roblox high school storyroblox high school story gameWebIntravenous Dose of Sodium Nitrite and Sodium Thiosulfate Adults . 1) Sodium Nitrite-10 mL of sodium nitrite at the rate of 2.5 to 5 mL/minute 2) Sodium Thiosulfate - 50 mL of sodium thiosulfate immediately following administration of sodium nitrite. Children . 1) Sodium Nitrite - 0.2 mL/kg (6 mg/kg or 6-8 mL/m. 2 roblox high school tricksWebSodium thiosulfate, commonly known as sodium thiosulphate, is a medicine that is used to treat cyanide poisoning, pityriasis versicolor, and cisplatin side effects. It is frequently used after the drug sodium nitrite for cyanide … roblox high top fade